Drug Class: 1st Generation Cephalosporins

Cefadroxil

MOA: cefadroxil binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis Brands of Cefadroxil registered in Kenya Actidrox®, Krishna Chemists Ltd Adora®,Incepta Pharmaceuticals Limited Biodroxil®, Sandoz GmbH Kundl Bidcef®, Plethico C-Drox®, Centurion Remedies Pvt. Ltd Curisafe®, Pharco Cedril®, …

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Cefazolin

Mechanism of Action Cefazolin is a bactericidal agent that acts by inhibition of bacterial cell wall synthesis. Resistance Predominant mechanisms of bacterial resistance to cephalosporins include the presence of extended-spectrum beta-lactamases and enzymatic hydrolysis. Antimicrobial Activity Cefazolin has been shown to be active against most isolates of the following microorganisms, both in vitro and in …

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Cephalexin

Brands names of Cephalexin in Kenya Alcephin®, Alembic C-Lex,Centurion Remedies Pvt Cefamor, Cadila pharmaceuticals (EA)Ltd Cefacure, Orchid Cefalexin, Medivet Products Ltd Cefalin, Flamingo Cephast ,Sterling Lab Cephastal, Stallion Cephoxin, Pharco Ceporex, GSK Corfex, Unosource Pharma Limited Felaxin, Crown Healthcare Felexin, Remedica Keflex, Eli Lilly Kelexin, Cosmos Ltd Leximark, Marksans Leocef, Lab and Allied Ltd Medalexin, …

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Cephradine

Brands of Cephradine ( Cefradine ) in Kenya Cefracef® ,Nirpo JMI Pharma Ltd Intracef®, Beximco Mechanism of Action: Cephradine disrupts the synthesis of the peptidoglycan layer forming the bacterial cell wall. The peptidoglycan layer is important for cell wall structural integrity. INDICATIONS: Respiratory tract infections (such as tonsillitis, pharyngitis, and lobar pneumonia) caused by group …

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