Mechanism of Action:
Cephradine disrupts the synthesis of the peptidoglycan layer forming the bacterial cell wall. The peptidoglycan layer is important for cell wall structural integrity.
Brands of Cephradine ( Cefradine ) in Kenya
Cefracef® ,Nirpo JMI Pharma Ltd
- Respiratory tract infections (such as tonsillitis, pharyngitis, and lobar pneumonia) caused by group A beta-hemolytic streptococci and S. pneumoniae (formerly D. pneumonia).
- Otitis media caused by group A beta-hemolytic streptococci, S. pneumoniae, H. influenzae, and staphylococci.
- Skin and skin structure infections caused by staphylococci (penicillin-susceptible and penicillin-resistant) and beta-hemolytic streptococci.
- Urinary tract infections, including prostatitis, caused by E. coli, P. mirabilis and Klebsiella species.
Cephradine is contraindicated in patients with known allergy to the cephalosporin class of antibiotics.
Clinical | Pharmacokinetic data
Routes of Administration:
Onset of Action:
Elimination Half life:
Legal Status | Dosage forms & Strengths
Narcotic Drugs and Psychotropic Substances (Control ) Act Schedule:
Dosage Forms | Strengths: