Mechanism of Action:

Cephradine disrupts the synthesis of the peptidoglycan layer forming the bacterial cell wall. The peptidoglycan layer is important for cell wall structural integrity.

Drug Label Information | Brands:

Brands of Cephradine ( Cefradine ) in Kenya

Cefracef® ,Nirpo JMI Pharma Ltd
Intracef®, Beximco


  • Respiratory tract infections (such as tonsillitis, pharyngitis, and lobar pneumonia) caused by group A beta-hemolytic streptococci and S. pneumoniae (formerly D. pneumonia).
  • Otitis media caused by group A beta-hemolytic streptococci, S. pneumoniae, H. influenzae, and staphylococci.
  • Skin and skin structure infections caused by staphylococci (penicillin-susceptible and penicillin-resistant) and beta-hemolytic streptococci.
  • Urinary tract infections, including prostatitis, caused by E. coli, P. mirabilis and Klebsiella species.


Cephradine is contraindicated in patients with known allergy to the cephalosporin class of antibiotics.