Paracetamol

BRANDS OF PARACETAMOL IN KENYA

Abpara, Abacus Pharma (A) Ltd

Ace , Square pharmaceutical Ltd

Acedol, Square Pharmaceuticals Ltd.

Arcet, Medisel Kenya Limited

Arfen, Medochemie Ltd.

Asmol, Astra Lifecare

Axapara, Axa Parenterals Ltd

Betamol, Sphinx Pharmaceuticals Ltd

Biomol , Biodeal Laboratories Ltd

Blink Infusion, Crown Healthcare

Calpol Suspension ,Glaxosmithkline Kenya Limited

Caremol, Careplus Ltd

Cetamol, Regal Pharmaceuticals Limited

Cipladon ,Cipla Ltd

Cosmol, Cosmos Limited

Curamol , Dawa Limited

Dolomol , Medox Pharmaceuticals Ltd

Elymol, Elys Chemical Industries Ltd

Febramol, Amanta Healthcare Limited

Feverex , Beta Healthcare International Limited

Feverex Toto , Beta Healthcare International Limited.

Fizzmol , Asence Pharma Private Limited

Fremol , Crown Healthcare

Kaldol , Leben Laboratories Pvt Ltd

Ifimol, Unique Pharmaceutical Laboratories

Infulgan , Yuria Pharma Ltd

Junior Sonadol, Orange Pharma Ltd

Jotonol, Benmed Pharmaceuticals Ltd

Micromol , National Pharmacy Ltd

Napa , Beximco Pharmaceuticals Ltd.

Neladol, Universal Corporation Limited

PA Injection , Lincoln Pharmaceuticals ltd

PA-12 , Lincoln Pharmaceuticals ltd

Painil, Njimia (K) Ltd

Panadol Actifast Soluble, Glaxosmithkline Kenya Limited

Panadol Advance ,Glaxosmithkline Kenya Limited

Panadol Baby & Infant ,Glaxosmithkline Kenya Limited

Panadol Elixir, Glaxosmithkline Kenya Limited

Parace , Zest Pharma

Paracetamol, Elys Chemical Industries Ltd

Paracetamol , Galpha Laboratories Ltd.

Paracerol, Polifarma İlac San. ve Tic. A.S

Paracetamol , Medopharm

Paracetamol B.Braun , B.Braun Melsungen Ag

Paracetamol, United Pharma (K) Limited

Paraconica, Acino pharma AG

Paratech, Themis Medicare Ltd

Paradol, Dinlaz Pharma EPZ Ltd

Para-Denk , Denk Pharma GmbH Co. KG

Parafast , Highchem Marketing Limited

Parafil , Fourrts (India) Laboratories Pvt. Limited

Paraflash, Nextgen Pharmaceuticals Ltd

Paralab , Laborate Pharmaceuticals India Limited

Paralief , Sai Pharmaceuticals Limited

Paratal, Laboratory & Allied Ltd

Paravin, MS Pharma Jordan

Parol , Dafra Pharma GmbH

Procet, Makupa Chemist Ltd

Regamol, Orange Pharma Ltd

Renova, Radiance Pharmaceuticals Ltd

Sonamol, Orange Pharma Ltd

Sanmol® 120 Child Effervescent Tablet ,PT Sanbe Farma

Sanmol® 500 Effervescent Tablet ,PT Sanbe Farma

Sanmol I.V Infusion ,PT Sanbe Farma

Sheladol , Shelys Pharmaceuticals Ltd.

Skymol, Skylight Chemical Industries

Tamin, ELDA International DMCC

Temol , Sandoz GmbH, Kundl

Thermodol , Unosource Pharma Ltd

Trumol, Questa Care Inc.

Totomol, Laboratory & Allied Ltd

Woodwards Paracetamol Syrup , Beta Healthcare International Limited.

Xykaa , Troikaa Pharmaceuticals Limited


Paracetamol in Kenya : Brands, Prices, Cost, Calpol, Panadol,Curamol,Cetamol
Paracetamol Chemical Structure

PARACETAMOL MODE OF ACTION:

Analgesic – the mechanism of analgesic action has not been fully determined. Paracetamol may act predominantly by inhibiting prostaglandin synthesis in the central nervous system (CNS) and to a lesser extent, through a peripheral action by blocking pain-impulse generation.

The peripheral action may also be due to inhibition of prostaglandin synthesis or to inhibition of the synthesis or actions of other substances that sensitise pain receptors to mechanical or chemical stimulation.

Antipyretic – paracetamol probably produces antipyresis by acting centrally on the hypothalamic heat-regulation centre to produce peripheral vasodilation resulting in increased blood flow through the skin, sweating and heat loss. The central action probably involves inhibition of prostaglandin synthesis in the hypothalamus.

INDICATIONS

For the treatment of mild to moderate pain including headache, migraine, neuralgia, toothache, sore throat, period pains, aches and pains, symptomatic relief of rheumatic aches and pains and of influenza, feverishness and feverish colds.

DOSAGE AND ADMINISTRATION

 

CONTRAINDICATIONS

Hypersensitivity to paracetamol or any of the constituents.

DRUG INTERACTIONS

Cholestyramine: The speed of absorption of paracetamol is reduced by cholestyramine. Therefore, the cholestyramine should not be taken within one hour if maximal analgesia is required.

Metoclopramide and Domperidone: The absorption of paracetamol is increased by metoclopramide and domperidone. However, concurrent use need not be avoided.

Warfarin: The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular use of paracetamol with increased risk of bleeding; occasional doses have no significant effect.

Chloramphenicol: Increased plasma concentration of chloramphenicol.

ADVERSE EFFECTS

Adverse effects of paracetamol are rare. Very rare cases of serious skin reactions have been reported. There have been reports of blood dyscrasias including thrombocytopenia purpura, methaemoglobenaemia and agranulocytosis, but these were not necessarily causality related to paracetamol.

Reporting of suspected adverse reactions:

The PPB Department of Pharmacovigilance was set up with a vision to develop, implement and continuously upgrade an appropriate system for detecting, reporting, and monitoring adverse drug reactions (ADRs) and other relevant problems with medicines in Kenya. The department strives to ensure the safety and efficacy of pharmaceutical products in Kenya.
Reporting suspected adverse reactions after authorization of the medicinal product are important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals/ Patients are encouraged to report any suspected adverse reactions via Pharmacovigilance Yellow Form, pv@pharmacyboardkenya.org or clicking below button:


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Clinical | Pharmacokinetic data


Pregnancy Category: A
Routes of Administration: By mouth, through the cheek, rectal, intravenous (IV)
Bioavailability: 63–89%
Protein Binding: 10–25%
Metabolosim: Predominantly in the liver
Onset of Action: By mouth – 37 minutes, Buccal – 15 minutes, Intravenous – 8 minutes
Elimination Half life: 2–2.5 hours
Excretion: Urine (85–90%)

Legal Status | Dosage forms & Strengths


Prescription Category:
OTC / Rx-only
Narcotic Drugs and Psychotropic Substances (Control ) Act Schedule:
This drug is not a controlled substance under Narcotic Drugs and Psychotropic Substances (Control ) Act
Dosage Forms | Strengths:


Drug Indentifiers:

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Drug Images

References/ Citation:




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