Zefcolin® Mode of Action
It has antitussive action for Symptomatic relief of Dry cough.
Manufactured by:
The Madras pharmaceuticals
for:
Fountil Life Sciences Pvt Ltd.
COMPOSITION:
Each 5ml Contains
Dextromethorphan Hydrobromide BP 10mg
Phenylephrine Hydrochloride BP 5mg
Cetirizine Hydrochloride BP 5mg
Racementhol BP 1.5mg
ACTION:
It has antitussive action for Symptomatic relief of Dry cough.
Dextromethorphan Hydrobromide is a cough suppressant ,which has Central action on the cough center in the medulla.It is used for the relief of non-productive dry cough.
Cetirizine Hydrochloride is an antihistamine reported to be long acting and with some mast cell stabilizing activity.It is used for the symptomatic relief of hypersensitivity reactions including rhinitis.
Phenylephrine Hydrochloride is the most commonly used salt for the symptomatic relief of nasal congestion.It is intended for the relief of cough and cold symptoms.
Menthol exerts a cooling and local analgesic effect on the irritated and inflamed respiratory mucosa,thereby reduces mucosal irritation and generation of tussal impulses.
INDICATIONS:
Zefcolin is indicated for symptomatic relief of dry unproductive cough due to post nasal drip,allergic & vasomotor rhinitis, Allergic pharyngitis, Laryngitis & sinusitis, Allergic cough following URTI and Surgery.
DOSAGE
5-10ml 2-3 times a day or as directed by physician.
SIDE EFFECTS:
Drowsiness,Dizziness,Nervousness and dry mouth.
Reporting of suspected adverse reactions:
The PPB Department of Pharmacovigilance was set up with a vision to develop, implement and continuously upgrade an appropriate system for detecting, reporting, and monitoring adverse drug reactions (ADRs) and other relevant problems with medicines in Kenya. The department strives to ensure the safety and efficacy of pharmaceutical products in Kenya.
Reporting suspected adverse reactions after authorization of the medicinal product are important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals/ Patients are encouraged to report any suspected adverse reactions via Pharmacovigilance Yellow Form, pv@pharmacyboardkenya.org or clicking below button:
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Clinical | Pharmacokinetic data
Pregnancy Category:
Routes of Administration: Oral
Bioavailability: Not Available
Protein Binding: Not Available
Metabolosim: Not Available
Onset of Action:
Elimination Half life: Not Available
Excretion: Not Available
Legal Status | Dosage forms & Strengths
Prescription Category:
Prescription only Medicine (POM) , â„ž-only
Narcotic Drugs and Psychotropic Substances (Control ) Act Schedule:
This Drug is not Subject to DDA drugs Act
Dosage Forms | Strengths:
Syrup
Drug Indentifiers:
Not availabe
Drug Images
References/ Citation:
- Bem, Jerzy L., and Richard Peck. “Dextromethorphan.” Drug Safety 7.3 (1992): 190-199.