Nitrofurantoin

Nitrofurantoin in Kenya

MOA: Nitrofurans interfere with cell metabolism and cell wall synthesis by inhibiting several enzyme systems including Acetyl Coenzyme A

Pharmacology & Brands Available:

Brands of Nitrofurantoin in Kenya:

Nitrofurantoin, Biodeal
Nitrofurantoin, Cosmos
Nitrofurantoin, Dawa
Nitrofurantoin, Elys
Nitrofurantoin, PMC
Nifuran®, Lab and Allied
Nitrofun®, Shelys

Indications / Dosage

Treatment of uncomplicated urinary tract infections (UTIs) and prophylaxis against UTIs in people prone to recurrent UTIs.It is effective against E. Coli, Enterobacter cystitis, Enterococcus, Klebsiella, and Staphylococcus aureus.

Adults and Pediatric Patients Over 12 Years:  100 mg every 12 hours for seven days.

Contra-Indications:

  • Hypersensitivity to nitrofurantoin
  • Renal Disorders
  • Porphyria
  • Pregnancy

Drug Interactions:

Antacids that contain magnesium trisilicate: These drugs can make nitrofurantoin less effective
Probenecid and sulfinpyrazone: Taking these drugs while you’re taking nitrofurantoin may cause harmful levels of nitrofurantoin to build up in your blood.

Side Effects of NitroFurantoin:

nausea, loss of appetite, diarrhoea, and headaches

Rarely numbness, lung problems, or liver problems may occur