Brands names of Linezolid in Kenya:

Arlin®, Beximco Pharmaceuticals Ltd
Bactolid®, Hetero Labs Ltd
Linospa®, Cipla
Linzo® , Medisel Kenya Limited.
Lizolid®, Glenmark Pharmaceuticals Limited
Lizomac®, Macleods Pharmaceuticals Limited
Lizomed®, Aglowmed Limited
Zyvox®, Pfizer

Linezolid in Kenya

Linezolid Mode of Action:

Linezolid binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit and prevents the formation of a functional 70S initiation complex, which is essential for bacterial reproduction.


Linezolid is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below. Linezolid is not indicated for the treatment of Gram-negative infections. It is critical that specific Gram-negative therapy be initiated immediately if a concomitant Gram-negative pathogen is documented or suspected
Nosocomial pneumonia caused by Staphylococcus aureus (methicillin-susceptible and -resistant isolates) or Streptococcus pneumoniae
Community-acquired pneumonia caused by Streptococcus pneumoniae, including cases with concurrent bacteremia, or Staphylococcus aureus (methicillin-susceptible isolates only)
Skin and Skin Structure Infections
Complicated skin and skin structure infections, including diabetic foot infections, without concomitant osteomyelitis, caused by Staphylococcus aureus (methicillin-susceptible and -resistant isolates), Streptococcus pyogenes, or Streptococcus agalactiae. Linezolid  has not been studied in the treatment of decubitus ulcers
Uncomplicated skin and skin structure infections caused by Staphylococcus aureus (methicillin-susceptible isolates only) or Streptococcus pyogenes.
Vancomycin-resistant Enterococcus faecium Infections
Vancomycin-resistant Enterococcus faecium infections, including cases with concurrent bacteremia


Known hypersensitivity to linezolid or any of the other product components.
Patients taking any monoamine oxidase inhibitors (MAOI) or within two weeks of taking an MAOI.


Monoamine Oxidase Inhibitors
Linezolid is a reversible, nonselective inhibitor of monoamine oxidase.
Adrenergic and Serotonergic Agents
Linezolid has the potential for interaction with adrenergic and serotonergic agents.


  • Myelosuppression: Monitor complete blood counts weekly. Consider discontinuation in patients who develop or have worsening myelosuppression.
  • Peripheral and optic neuropathy: Reported primarily in patients treated for longer than 28 days. If patients experience symptoms of visual impairment, prompt ophthalmic evaluation is recommended.
  • Serotonin syndrome: Patients taking serotonergic antidepressants should receive linezolid only if no other therapies are available. Discontinue serotonergic antidepressants and monitor patients for signs and symptoms of both serotonin syndrome and antidepressant discontinuation.
  • A mortality imbalance was seen in an investigational study in linezolid-treated patients with catheter-related bloodstream infections.
  • Clostridium difficile associated diarrhea: Evaluate if diarrhea occurs.
  • Potential interactions producing elevation of blood pressure: monitor blood pressure.
  • Hypoglycemia: Postmarketing cases of symptomatic hypoglycemia have been reported in patients with diabetes mellitus receiving insulin or oral hypoglycemic agents.


Most common adverse reactions (>5% of adult and/or pediatric patients treated with linezolid) include: diarrhea, vomiting, headache, nausea, and anemia

Reporting of suspected adverse reactions:

The PPB Department of Pharmacovigilance was set up with a vision to develop, implement and continuously upgrade an appropriate system for detecting, reporting, and monitoring adverse drug reactions (ADRs) and other relevant problems with medicines in Kenya. The department strives to ensure the safety and efficacy of pharmaceutical products in Kenya.
Reporting suspected adverse reactions after authorization of the medicinal product are important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals/ Patients are encouraged to report any suspected adverse reactions via Pharmacovigilance Yellow Form, or clicking below button:

Linezolid in Kenya
Linezolid in Kenya
Linezolid in Kenya
Linezolid in Kenya
Linezolid in Kenya

How to find Zyvox for sale in Kenya

Clinical | Pharmacokinetic data

Pregnancy Category: C (Risk not ruled out)
Routes of Administration: Intravenous infusion, by mouth
Bioavailability: ~100% (oral)
Protein Binding: Low (31%)
Metabolosim: liver (50–70%, CYP not involved)
Onset of Action: Not Available
Elimination Half life: 3–7 hours; longer half-life in CSF than plasma
Excretion: non-kidney, kidney, and fecal

Legal Status | Dosage forms & Strengths

Prescription Category:
Prescription only Medicine (POM) , ℞-only
Narcotic Drugs and Psychotropic Substances (Control ) Act Schedule:
This drug is not a controlled substance under Narcotic Drugs and Psychotropic Substances (Control ) Act
Dosage Forms | Strengths:
600mg Tablets | 300ml infusion bag , 2mg per ml | Suspension 100mg/ 5ml

Drug Indentifiers:

CAS Number
PubChem CID
PDB ligand
CompTox Dashboard (EPA)
ECHA InfoCard

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References/ Citation:

Side Effect

Suspected health product

At the time of the side effect, specify:

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