Fosfomycin

Brands of Fosfomycin

Focin®, Tabros
Fosmol, Pharma Bavaria International


Fosfomycin in Kenya: brand names , Prices,Cost
Fosfomycin in Kenya

INDICATIONS:

Fosfomycin is indicated for the treatment of the following infections in adults and children including neonates :

– Osteomyelitis

– Complicated urinary tract infections

– Nosocomial lower respiratory tract infections

– Bacterial meningitis

– Bacteraemia that occurs in association with, or is suspected to be associated with, any of the infections listed above. 

Fosfomycin should be used only when it is considered inappropriate to use antibacterial agents that are commonly recommended for the initial treatment of the infections listed above, or when these alternative antibacterial agents have failed to demonstrate efficacy.

Consideration should be given to official guidance on the appropriate use of antibacterial agents.

CONTRAINDICATIONS:

Fosfomycin is contraindicated in patients with known hypersensitivity to the drug.

DRUG INTERACTIONS

No drug-drug interaction studies have been performed with fosfomycin. To date, no clinically relevant pharmacological interactions between fosfomycin and other agents (drugs, stimulants or foodstuffs) have been reported.

Combination with other antibiotics

In-vitro tests have shown that the combination of fosfomycin with a β-lactam antibiotic such as penicillin, ampicillin, cefazolin or the class of carbapenems, usually shows an additive to synergistic effect. The same applies to the combination of fosfomycin with most anti-staphylococcal (linezolid, quinupristin/dalfopristin, moxifloxacin) agents in the treatment of staphylococcal infections. The combination of fosfomycin with aminoglycosides has predominantly indifferent to additive effects.

ADVERSE DRUG REACTIONS:

angioedema, aplastic anemia, asthma (exacerbation), cholestatic jaundice, hepatic necrosis, and toxic megacolon.
anaphylaxis and hearing loss.

Reporting of suspected adverse reactions:

The PPB Department of Pharmacovigilance was set up with a vision to develop, implement and continuously upgrade an appropriate system for detecting, reporting, and monitoring adverse drug reactions (ADRs) and other relevant problems with medicines in Kenya. The department strives to ensure the safety and efficacy of pharmaceutical products in Kenya.
Reporting suspected adverse reactions after authorization of the medicinal product are important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals/ Patients are encouraged to report any suspected adverse reactions via Pharmacovigilance Yellow Form, pv@pharmacyboardkenya.org or clicking below button:


Fosfomycin in Kenya
Fosfomycin in Kenya
brand names of Fosfomycin in Kenya
Where to buy Fosfomycin in Kenya
Price of Fosfomycin in Kenya

Clinical | Pharmacokinetic data


Pregnancy Category: B (No risk in non-human studies)
Routes of Administration: Oral
Bioavailability: 30–37% (by mouth, fosfomycin tromethamine); varies with food intake
Protein Binding: Nil
Metabolosim: Nil
Onset of Action: Not Available
Elimination Half life: 5.7 hours (mean)
Excretion: Kidney and fecal, unchanged

Legal Status | Dosage forms & Strengths


Prescription Category:
Prescription only Medicine (POM) , ℞-only
Narcotic Drugs and Psychotropic Substances (Control ) Act Schedule:
This drug is not a controlled substance under Narcotic Drugs and Psychotropic Substances (Control ) Act
Dosage Forms | Strengths:
3000mg granules for Oral solution

Drug Indentifiers:

CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard


Drug Images

References/ Citation:




What was the patient being treated for
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