Clindamycin

Clindamycin Chemical Structure: Clindamycin in Kenya

MOA: Suppresses protein synthesis by binding to 50S ribosomal subunits;

Pharmacology & Brands Available:

Brands of Clindamycin in Kenya

Clindar-B®, Wallace Pharmaceuticals PVT Limited
Clindacin®, Flamingo Pharmaceuticals Ltd.
Dacillin® ,Life Sciences PVT. Ltd
Dalacin-C®, Pfizer

Clindamycin was first made in 1966 or 1967.It is on the Kenya Essential Medicines List , which lists the most effective ,cost effective and safe medicines needed in a health system in Kenya.

Indications

Clindamycin is used primarily to treat anaerobic infections caused by susceptible anaerobic bacteria, including dental infections,and infections of the respiratory tract, skin, and soft tissue, and peritonitis.

Drug interactions

  • clindamycin decreases effects of BCG vaccine live by pharmacodynamic antagonism.
  • clindamycin decreases effects of typhoid vaccine live by pharmacodynamic antagonism
  • clindamycin increases effects of Neuromascular Junction Blockers by pharmacodynamic synergism.
  • nitazoxanide, clindamycin.
    Either increases levels of the other by Mechanism: plasma protein binding competition

Adverse Drug Effects of Clindamycin

  • Abdominal pain
  • Agranulocytosis
  • Eosinophilia
  • Fungal overgrowth
  • Pseudomembranous colitis
  • Hypersensitivity
  • Rashes
  • Urticaria
  • Hypotension

You can get Cindamycin at Registered chemist near you