Drug Class: Macrolides

Erythromycin

Mechanism of Action Erythromycin and other macrolide antibiotics inhibit protein synthesis by binding to the 23S rRNA molecule (in the 50S subunit) of the bacterial ribosome blocking the exit of the growing peptide chain of sensitive microorganism Mechanism of Resistance The major route of resistance is modification of the 23S rNA in the 50S ribosomal …

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Azithromycin

Brands of Azithromycin in Kenya Agycin, Bliss GVS Pharma Ltd. ATM, Indoco Remedies Limited Azal, Medox Pharmaceuticals Ltd Azaltic , Nirpo Jmi Pharma Ltd Azar, Ochoa Azbact , Globela Pharma Pvt. Ltd Azi-Agio, Agio Azi-bio , Sava Healthcare Ltd Azibru , Brawn Laboratories Limited Azic ,Cian Health Care Pvt. Ltd. Azicin, Opsonin Azicip, Cipla Ltd …

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Clarithromycin

Brand names of Clarithromycin in Kenya Acem, Emcure Pharmaceuticals Ltd Aziclar, Flamingo Cipclar, Cipla Ltd Claranta, Ajanta Pharma Limited Claricor, Coral Claricos, Cosmos Limited Claridar, Dar Clarie, Indswift Limited Claritek, Getz Pharma (Pvt) Limited Clarimet, Metro Claranta, Ajanta Clarifred, Fredun Pharmaceutical Ltd Clarimin , Kopran Limited Clarithro, Alembic Clarithromycin, Metro Claritron, Strides Arcolab Limited Clariwin, …

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Spectinomycin

Brands Spectinomycin in Kenya: Gono®, Lab and Allied Togamycin®, Pfizer Togozed®, Zawadi Healthcare Ltd Mechanism of Action : Inhibits protein synthesis in bacterial cell by binding reversibly to the P site on the 50S subunit of the bacterial ribosome. This action is considered to be bacteriostatic INDICATIONS: Gonorrhea caused by penicillin-resistant bacteria or in patients …

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Fidaxomicin

Brands of Fidaxomicin in Kenya NB: Fidaxomicin is not available in Kenyan market Fidaxomicin Mechanism of Action: Fidaxomicin is a fermentation product obtained from the Actinomycete Dactylosporangium aurantiacum. Fidaxomicin is bactericidal against C. difficile in vitro, inhibiting RNA synthesis by RNA polymerases, and demonstrates a post-antibiotic effect vs. C. difficile of 6-10 hrs. INDICATIONS AND …

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Azithromycin/ Fluconazole/ Secnidazole

Brands of Azithromycin / Fluconazole / Secnidazole in Kenya: BTC Kit®, Lincoln Pharmaceuticals Ltd Combisaf® , Shambhuprasad And Sons Dazel kit®, Ajanta Pharma Limited G-CURE®, Fredun Pharmaceutical Ltd Gynagone Kit®, Laboratory & Allied Gynokit®, Plethico Gyncure Kit®, PSM Pharmaceuticals Ltd Her Kit®, Zawadi Healthcare Ltd UTI®, United Pharma (K) Limited Vastkit® , Daima Dispensing Chemists …

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