Drug Class: H2-Antagonists

Cimetidine

Mechanism of Action: Cimetidine is a histamine H2-antagonist and inhibits actions of histamine mediated by H2-receptors such as gastric acid secretion and pepsin output. Brands of Cimetidine Cemet®, Cosmos Ltd Labcimet®,Lab and Allied Medicit® , Medisel Tagamet®, GSK Ulcidin®,West Coast Ulmet® , Universal Corporation Limited Pharmacokinetics: Cimetidine is readily absorbed from the gastro-intestinal tract and …

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Famotidine

Famotidine is a competitive inhibitor of histamine H2-receptors. The primary clinically important pharmacologic activity of famotidine is inhibition of gastric secretion. Both the acid concentration and volume of gastric secretion are suppressed by famotidine, while changes in pepsin secretion are proportional to volume output. Brands of Famotidine Acicep®, Kopran Famotidine, Teva Famotidine, Ulcofam Yamadin®, Beximco …

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Ranitidine

Ranitidine is a competitive, reversible inhibitor of the action of histamine at the histamine H2-receptors, including receptors on the gastric cells. Ranitidine does not lower serum Ca++ in hypercalcemic states. Ranitidine is not an anticholinergic agent. Brands of Ranitidine in Kenya Aciloc®,Cadila Labtac®, Lab and Allied Ranitidine, Metro Reduced®, Flamingo R-loc®, Zydus Neoceptin-R®,Beximco Neotack®,Square Ranidin®,ACME …

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Nazitidine

Mechanism of Action: Nizatidine is a competitive, reversible inhibitor of histamine at the histamine H2-receptors, particularly those in the gastric parietal cells. Nizatidine is a histamine H2 receptor antagonist that inhibits stomach acid production, and is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. Nizatidine was developed by Eli Lilly, …

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