Drug Class: 3rd Generation Fluoroquinolones

Sparfloxacin

MOA: Fluoroquinolones act by inhibiting two enzymes involved in bacterial DNA synthesis, both of which are DNA topoisomerases that human cells lack and that are essential for bacterial DNA replication, thereby enabling these agents to be both specific and bactericidal Brands of Sparfloxacin in Kenya: Sparbact®, IPCA Sparflo®, Dr.Reddy Sparta®,Alembic Sparx®, Wockhardt INDICATIONS: Community-acquired pneumonia …

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Pefloxacin

MOA : Pefloxacin (or Fluoroquinolones in general act by inhibiting two enzymes involved in bacterial DNA synthesis, both of which are DNA topoisomerases that human cells lack and that are essential for bacterial DNA replication, thereby enabling these agents to be both specific and bactericidal. Brands of  Pefloxacin in Kenya Pefaxin®, Emil Peflobid®, Cadila pharm …

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