Drug Class: β-lactamase inhibitors

Cefoperazone + Sulbactam

Mechanism of Action Cefoperazone exerts its bactericidal effect by inhibiting the bacterial cell wall synthesis, and sulbactam acts as a beta-lactamase inhibitor, to increase the antibacterial activity of cefoperazone against beta-lactamase-producing organisms. Brands of Cefoperazone in Kenya Bactacef, Swiss Parenterals (Pvt.) Ltd Cebanex, Orchid Cefobact ,Inject Care Parenterals Pvt. Ltd Cefocel, Zawadi Healthcare Ltd Cesalac, …

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Ceftriaxone / Sulbactum

Mechanism of Action Ceftriaxone is a bactericidal agent that acts by inhibition of bacterial cell wall synthesis. Ceftriaxone has activity in the presence of some beta-lactamases, both penicillinases and cephalosporinases, of Gram-negative and Gram-positive bacteria. Sulbactam is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the …

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